Plant Transcription Factor Database
Previous version: v3.0
Gossypium hirsutum
SBP Family
Species TF ID Description
Gh_A01G0447SBP family protein
Gh_A01G0812SBP family protein
Gh_A01G1274SBP family protein
Gh_A01G1281SBP family protein
Gh_A01G2095SBP family protein
Gh_A02G0446SBP family protein
Gh_A02G0579SBP family protein
Gh_A02G1694SBP family protein
Gh_A03G0632SBP family protein
Gh_A03G1083SBP family protein
Gh_A03G1092SBP family protein
Gh_A04G1266SBP family protein
Gh_A04G1331SBP family protein
Gh_A04G1486SBP family protein
Gh_A07G0442SBP family protein
Gh_A07G1375SBP family protein
Gh_A08G0326SBP family protein
Gh_A10G0934SBP family protein
Gh_A10G2217SBP family protein
Gh_A11G0344SBP family protein
Gh_A11G0706SBP family protein
Gh_A11G0943SBP family protein
Gh_A11G2811SBP family protein
Gh_A12G0866SBP family protein
Gh_A12G0867SBP family protein
Gh_A12G1096SBP family protein
Gh_A12G1380SBP family protein
Gh_A13G0749SBP family protein
Gh_A13G1251SBP family protein
Gh_D01G0457SBP family protein
Gh_D01G0839SBP family protein
Gh_D01G1229SBP family protein
Gh_D01G1495SBP family protein
Gh_D01G1503SBP family protein
Gh_D02G0498SBP family protein
Gh_D02G0637SBP family protein
Gh_D02G1306SBP family protein
Gh_D02G1499SBP family protein
Gh_D02G1515SBP family protein
Gh_D03G0025SBP family protein
Gh_D03G0920SBP family protein
Gh_D04G1827SBP family protein
Gh_D04G1893SBP family protein
Gh_D04G1985SBP family protein
Gh_D07G0506SBP family protein
Gh_D07G1479SBP family protein
Gh_D08G0423SBP family protein
Gh_D10G0251SBP family protein
Gh_D10G1634SBP family protein
Gh_D11G0401SBP family protein
Gh_D11G0821SBP family protein
Gh_D11G1088SBP family protein
Gh_D11G3165SBP family protein
Gh_D12G0947SBP family protein
Gh_D12G0948SBP family protein
Gh_D12G1220SBP family protein
Gh_D12G1504SBP family protein
Gh_D13G0874SBP family protein
Gh_D13G1551SBP family protein
Gh_Sca035233G01SBP family protein
Gh_Sca067845G01SBP family protein
Gh_Sca129122G01SBP family protein
SBP Family Introduction

SQUAMOSA promoter binding proteins (SBPs) form a major family of plant-specific transcription factors related to flower development. Although SBPs are heterogeneous in primary structure, they share a highly conserved DNA-binding domain (DBD) that has been suggested to be zinc binding. Here we report the NMR solution structures of DBDs of two SBPs of Arabidopsis thaliana, SPL4 and SPL7. The two share essentially the same structural features. Each structure contains two zinc-binding sites consisting of eight Cys or His residues in a Cys3HisCys2HisCys or Cys6HisCys sequence motif in which the first four residues coordinate to one zinc and the last four coordinate to the other. These structures are dissimilar to other known zinc-binding structures, and thus represent a novel type of zinc-binding motif. The electrostatic profile on the surface suggested that a continuous region, including all the conserved basic residues, is involved in the DNA binding, the mode of which is likely to be novel as well.

Yamasaki K, Kigawa T, Inoue M, Tateno M, Yamasaki T, Yabuki T, Aoki M, Seki E, Matsuda T, Nunokawa E, Ishizuka Y, Terada T, Shirouzu M, Osanai T, Tanaka A, Seki M, Shinozaki K, Yokoyama S.
A novel zinc-binding motif revealed by solution structures of DNA-binding domains of Arabidopsis SBP-family transcription factors
J Mol Biol. 2004 Mar 12;337(1):49-63.
PMID: 15001351

SBP-box genes were first characterized as SQUAMOSA promoter binding proteins (SBPs) to regulate the expression of MADS-box genes in early flower development of A. majus (Klein et al., 1996). Since then, SBP-box genes have been identified in many plants including green alga, moss, silver birch, A. majus, Arabidopsis and maize. They play critical roles in regulating flower and fruit development as well as other physiological processes ([Moreno et al., 1997],[Eriksson et al., 2004], [Lannenpaa et al., 2004], [Arazi et al., 2005] and [Kropat et al., 2005]). It has been reported that Arabidopsis SPL3, SPL8 and SPL14 involves in flowering, sporogenesis, GA signaling and toxin resistance ([Cardon et al., 1997], [Unte et al., 2003], [Stone et al., 2005] and [Zhang et al., 2006]) while maize tga1 and tomato LeSPL-CNR affect fruit development ([Wang et al., 2005a] and [Manning et al., 2006]).

SBP-box genes encode proteins sharing a conserved DNA-binding domain of 79 amino acid residues. It has been proved that the DNA-binding domain of SBP-box genes is necessary and sufficient to bind to a palindromic GTAC core motif ([Klein et al., 1996], [Cardon et al., 1997], [Cardon et al., 1999], [Lannenpaa et al., 2004] and [Birkenbihl et al., 2005]). Studies on the NMR solution structure of the fragment of Arabidopsis SPL4 and SPL7 revealed that the DNA-binding domain of SBPs consisted of two separate zinc-binding sites. One zinc finger is C3H or C4 and the other is C2HC (Yamasaki et al., 2004 K. Yamasaki et al.,).

Guo AY, Zhu QH, Gu X, Ge S, Yang J, Luo J.
Genome-wide identification and evolutionary analysis of the plant specific SBP-box transcription factor family.
Gene. 2008 Jul 15;418(1-2):1-8.
PMID: 18495384